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1    Brockmann H und Bode J (1971) WidersprĂŒchliche Ergebnisse bei Konfigurationsbestimmungen durch kinetische Racematspaltung. Liebigs Ann. Chem. 748:20-25.
2      Bode J und Brockmann H (1972) Zur relativen Konfiguration 2.3-Dialkyl-substituierer BernsteinsĂ€uren.Chem. Ber. 105:34-44
3      Brockmann H und Bode J (1974)  Bestimmung der absoluten Konfiguration von Chlorophyll a nach der Methode von Horeau. Liebigs Ann. Chem. 1974:1017-1027.
4      Raftery MA, Vandlen R, Michaelson D, Bode J, Moody T, Chao Y, Reed K, Deutsch J & Duguid J (1974) The biochemistry of an acetylcholine receptor. J. Supramolec. Struc. 2:582-592. .
5      Raftery MA, Bode J, Vandlen R, Michaelson D, Deutsch J & Moody T (1974) “Characterization of acetylcholine receptors”. Proc. Mosbach Colloq. L. Jaenicke, ed.. pp 541-564
6      Michaelson  D, Vandlen R, Bode J, Moody T, Schmidt J &  Raftery MA (1974)  Some molecular properties of an isolated acetylcholine receptor ion-translocation protein Arch. Biochem. Biophys. 165:796-804. PDF (725 K)
7      Raftery MA, Bode J, Vandlen R, Michaelson D, Deutsch J, Moody T, Ross MJ & . Stroud RM. (1974) Sund H, ed.. “Structural and functional studies of an acetylcholine receptor”. Symp. on Protein-Ligand Interactions, Konstanz 328-355,
8      Reed K, Vandlen R, Bode J, Duguid J & Raftery MA. (1975) Characterization of Acetylcholine-Receptor-Rich and acetylcholine-esterase-rich particles from torpedo californica electroplax. Arch. Biochem. Biophys. 167:138-144. . PDF (1628 K)
9      Bode J, Blumenstein M & Raftery MA (1975) Non-identical alkylation sites in rabbit muscle glyceraldehyde-3-phosphate dehydrogenase. Biochemistry 14:1146-1152PDF
10     Bode J, Blumenstein M & Raftery MA. (1975) 19F Nuclear magnetic resonance studies of structure and function relationships in trifluoroacetonylated rabbit muscle glyceraldehyde-3-phosphate dehydrogenase. Biochemistry 14:1153-1160. PDF
11     Bode J & Wagner KG (1975)  The use of subunit-exchange chromatography for the group-specific fractionation of histones. Biochem. Biophys. Res. Comm. 62, 868-876. PDF (615 K)
12     Bode J & Willmitzer L (1975) Application of fluorescamine to the study of protein-DNA-interactions. Nucleic Acids Res. 2:1951-1965. PDF (1.0M) .
13     Gorenstein DG, Wyrwicz AM & Bode J (1976) The interaction of uridine and cytidine monophosphates with ribonuclease; 31P-NMR Studies. J. Amer. Chem. Soc. 98:2308-2314. PDF
14     Wagner KG, Bode J, K. Wehling & L. Willmitzer (1976)  Sperm-specific proteins; interaction with DNA and chromatin and influence of phosphorylation thereon. Stud. Biophys. 55:39-48.
15     Wagner KG, H. A. Arfmann, Bode J, K. Wehling & L. Willmitzer (1976). The interaction of basic proteins with DNA and chromatin. development of new methods. Nucleic Acids and Protein Synthesis in Plants - Colloques Internationaux du Centre National de la Recherche Scientifique (CNRS), Strasbourg 261:103-107.
16     Bode J, L. Willmitzer & K. Opatz (1977) On the competition between protamines and histones: studies directed towards the understanding of spermiogenesis. Eur. J. Biochem. 72:393-403.
17     L. Willmitzer, Bode J & Wagner KG (1977)  “Phosphorylated pProtamines I. Binding stoichiometry and thermal stability of complexes with DNA”. Nucleic Acids Res. 4:149-162. PDF
18     L. Willmitzer, Bode J & Wagner KG (1977)  “Phosphorylated protamines II. Circular dichroism of complexes with DNA; dependency on ionic strength. Nucleic Acids Res. 4:163-176. PDF (911K) 
19     Bode J & Lesemann D (1977)  The anatomy of cooperative binding between protamines and DNA”. Hoppe Seyler's Z. Physiol. Chem. 358:1505-15121.
20     Wagner KG, Bode J, K.-W. Hofmann & L. Willmitzer (1978) Studies on the mechanism of DNA condensation by basic chromosomal proteins. Stud. Biophys. 67:85 (Microfiche 2/7-16).
21     Bode J & Standt UD (1978)  Structural aspects of histone complexes and nucleosomes revealed by the accessibility of cysteine side chains. Z. Naturforsch. 33c:884-890.
22     Bode J (1979) Inter- and intramolecular crosslinks in histone H3 induced by 5,5'-Dithiobis-(2-nitrobenzoic acid). Analyt. Biochem. 94: 465-469.
23     Bode J, Moody T, . Schimerlik M & Raftery MA (1979) Uses of fluorescent cholinergic analogues to study binding sites for cholinergic ligands in Torpedo Californica acetylcholine receptor. Biochemistry 18:1855-1861. PDF
24     Bode J, Willmitzer L, Arfmann HA & Wehling K (1979).  Condensation of DNA and chromatin by histones H1, H5 and protamines; the influence of a protein phosphorylation. Int. J. of Biol. Macromol. 1:73-78.
25     Bode J (1979). On the reactions of Fluorescamine with chromosomal proteins”. Analyt. Biochem. 99:274-280
26     Hofmann KW, Arellano A, Arfmann HA & Bode J (1980) Modulation of histone H5-nucleosome interactions by H5 phosphorylation. Int. J. Biol. Macromol. 2:25-32.
27     Bode J, Schröter H & Maass K (1980) Dissolvable disulfide-polyacrylamide gels for the electrophoretic analysis of chromosomal proteins and for affino-electrophoresis of thiol-proteins. J. Chromatog. 190:437-444.
28     Arfmann HA & Bode J (1980) “Specificity of histone phosphorylation. Influence of nucleosome structure”. Int. J. Biol. Macromol. 2: 109-112.
29     Bode J & Henco H (1980) Prepartion and properties of a nucleosomal particle containing 180 base pairs of DNA. Int. J. Biol. Macromol. 2:122-128.
30     Bode J & Wagner KG (1980) The cooperative exposure of histone H3 thiols in core particles. Int. J. Biol. Macromol. 2:129-136
31     Bode J, Henco K & Wingender E (1980)  Modulation of the nucleosome structure by histone acetylation. Eur. J. Biochem. 110:143-152.
32     Bode J (1980). “Biotechnologische Anwendung Tierischer Zellkulturen”. In: Handbuch der Biotechnologie PrĂ€ve P, Faust A, Sittig W, ed., 1. Auflage (1980). Akademischen Verlagsgesellschaft. 2. Auflage (1984) im Oldenbourg Verlag. 3. neugefasste Auflage (1986) im Oldenbourg Verlag.
33     GĂłmez-Lira MM & Bode J (1981) Effects of butyrate upon the metaphase-specific deacetylation of histone H4. FEBS Lett. 127:228-232.
34     Schröter H, GĂłmez-Lira MM, Plank KH & Bode J (1981) The extent of histone acetylation induced by butyrate and the turnover of acetyl groups depend on the cell line.Eur. J. Biochem. 120:21-28
35     Wingender E, Maass K & Bode J (1981)  Influence of cysteine-specific labels upon the stability of nucleosomes. Int. J. Biol. Macromol. 3:114-120.
36     Bode J, Wingender E & Plank KH (1982) Parameters affecting the superreactivity of the cysteine side chains in histone H3; characterization of a 32-amino-acid peptide including Cys-110. Eur. J. Biochem. 123:23-28.
37     Bode J, H. K. Hochkeppel & Maass K (1982) Links between the effects of butyrate on histone hyperacetylation and the regulation of interferon synthesis in Namalva and FS-4 cell lines. J. Interferon Res. 2:159-166.
38     H. Schröter & Bode J (1982) The binding sites for large and small HMG proteins. Studies on HMG-nucleosome interactions in vitro. Eur. J. Biochem. 127:429-436.
39     Bode J, GĂłmez-Lira MM & Schröter H (1983)  Nucleosomal particles open as the histone core becomes hyperacetylated. Eur. J. Biochem. 130: 437-445.
40     Bode J (1984) . Nucleosomal conformations induced by the small HMG proteins or by histone hyperacetylation are distinct. Arch. Biochem. Biophys. 228, 354-372
41     Burggraf E, Erard M, GĂłmez-Lira MM & Bode J (1984)  Influence of histone hyperacetylation on nucleosomal particles as visualized by electron microscopy Arch Biochem. Biophys. 229:395-398..
42     Bode J, Pucher HJ & Maass K (1986)  Chromatin structure and induction-dependent conformational changes of human interferon-beta genes in a mouse host cell. Eur. J. Biochem. 158, 393-401.
43     Berlin J & Bode J (1987) ”Plant and animal tissue culture”. In Fundamentals of Biotechnology, PrĂ€ve P, Faust U & Sukatsch DA , ed., Verlag Chemie, pp 133-177, ISBN 3-527-26144-3.
-      ”Tissue culture”. In "Basic Biotechnology - a Student's Guide", PrĂ€ve P, Faust U & Sukatsch DA, ed., Verlag Chemie, pp 133-177, ISBN 3-527-26678-X.
44     Klehr D & Bode J (1988) Comparative evaluation of bovine papilloma virus (BPV): vectors for the study of gene expression in mammalian cells. Mol. Gen. (Life Science Adv.) 7: 47-52.
45     Bode J & Maass K (1988) The chromatin domain surrounding the human interferon-beta gene as defined by scaffold-attached regions (SARs). Biochemistry 27: 4706-4711. PDF
46     Wirth M, Bode J,  Zettelmeißl G & Hauser H (1988) “Isolation of overproducing recombinant mammalian cell lines by a fast and simple selection procedure”. Gene 73:419-426. PDF (969 K)
47     Bode J & H. Hauser (1990, 1992) “Biologische Wirkungen und  Induktionsmechanismen der Interferone”. In: Jahrbuch Biotechnologie, B& 3, pp 63-100, Praeve P, Schlingmann M, Crueger W, Esser K, Thauer R & Wagner F, ed., Carl Hanser Verlag MĂŒnchen.
-      “Interferons: Biological Activities and Induction Mechanisms”. In Biotechnology Focus, 3rd edition, pp 57-93, PrĂ€ve P, Schlingmann M, Crueger W, Esser K, Thauer R & Wagner F, ed., Carl Hanser Verlag MĂŒnchen
48     Mielke C, Kohwi Y, Kohwi-Shigematsu T & Bode J (1990) Hierarchical binding of DNA fragments derived from scaffold-attached regions: correlation of properties in vitro and function in vivo. Biochemistry 29, 7475-7485. PDF
49    Artelt P, Bode J, Wirth M & Hauser H (1990). “Biologische Sicherheit im Umgang mit genetisch manipulierten SĂ€ugerzellen”,  In: Biologische Sicherheit, 2:289- 302, Weber E, ed.,  BMFT, Bonn.
50     Klehr D, Maass K & Bode J (1991) Scaffold-attached regions from the human IFN-beta domain can be used to enhance the stable expression of genes under the control of various promoters. Biochemistry 30, 1264-1270. PDF
51     Rzepecki R, Smidzinski R, Bode J & Szopa J (1992),  The 65 kDa protein affected endonuclease tightly associated with plant nuclear matrix. J. Plant Physiol. 139, 284-288.
52     Bode J, Kohwi Y, Dickinson L, Joh T, Klehr D, Mielke C & Kohwi-Shigematsu T (1992) Biological significance of unwinding capability of nuclear matrix-associating DNAs. Science 255, 195-197.Full Text (PDF)
53     Klehr D, Schlake T, Maass K & Bode J (1992),  Scaffold-attached regions (SAR elements) mediate transcriptional effects due to butyrate. Biochemistry 31:3222-3229. PDF
54     J. Szopa, Bode J, V. Kay, A. Kozubek & A. F. Sikorski (1993) Does a prototype scaffold/matrix-attached region (SAR sequence)  affect intrinsic nuclear matrix endonuclease specificity? J. Plant Physiol. 141:668-672 (1993)
55     V. Kay & Bode J (1994), Binding specificities of a nuclear scaffold: Supercoiled, single stranded and SAR-DNA. Biochemistry 33:367-374. PDF
56     Schlake T, Klehr-Wirth D, Yoshida M, Beppu T & Bode J (1994) Gene expression within a chromatin domain: The role of core histone hyperacetylation. Biochemistry, 33:4197-4206. PDF
57     Artelt P, Bode J, Mielke C, Grannemann R, Heinemeyer T, Klehr D, Wirth M & Hauser H (1994). “Biologische Sicherheit im Umgang mit genetisch manipulierten SĂ€ugerzellen”,  In: Biologische Sicherheit, 3: 463-502, BMFT, Bonn
58     A. Dietz, V. Kay, Schlake T, J. Landsmann & Bode J (1994) A Plant scaffold attachment region detected close to a T-DNA integration site is active in mammalian cells. Nucleic Acids Res. 22, 2744-2751. PDF
59     Schlake T & Bode J (1994) Use of mutated FLP-recognition-target-(FRT-)sites for the exchange of expression cassettes at defined chromosomal loci. Biochemistry (accel. pub.) 33:12746-12751.
60     Bode J, Schlake T, RĂ­os-RamĂ­rez M, Mielke C, Stengert M, Kay V & Klehr-Wirth D (1995) Scaffold/matrix-attached regions: structural properties creating transcriptionally active loci. In: Structural and Functional Organization of the Nuclear Matrix.. Berezney R & Jeon KW, ed., International Review of Cytology, Vol 162A:389-453. Academic Press.
-      Bode J, Schlake T., RĂ­os-RamĂ­rez M., Mielke C., Stengert, M., Kay, V & Klehr-Wirth, D (1997) Scaffold/matrix-attached regions: structural properties creating transcriptionally active loci". In: Nuclear Matrix, R”. Berezney ed., Academic Press, pp 389-453 (1997).
61     Kay V & Bode J (1995) Detection of scaffold-attached  regions (SARs) by in vitro techniques; activities of these elements in vivo. In: Methods in Molecular and Cellular Biology 5:186-194 -  Methods for studying DNA-protein interactions - an overview,  Papavassiliou AG., & King S L, eds. Inc. Wiley-Liss
62     Mielke C, Tuemmler M & Bode J (1995)  Fast, inexpensive and reproducible assay for puromycin N-acetyltransferase: Selection marker used as a reliable reporter. Trends in Genetics 11:258-259. http:/ PDF (278 K)
63     Mielke C, Maass K, Tuemmler M & Bode J (1996) Anatomy of highly-expressing chromosomal sites targeted by retroviral vectors. Biochemistry 35:2239-2252. PDF
64     Bode J, Stengert-Iber M, Schlake T, Kay V & Dietz-Pfeilstetter A (1996) Scaffold/matrix-attached regions: topological switches with multiple regulatory functions. Crit. Rev. Eukaryot. Gene Expression 6:115-138.
65     Dietz-Pfeilstetter A, Kay V, Landsmann J & Bode J (1996) “Characterization of a plant scaffold attached region (SAR) from a T-DNA integration site”. In: Biosafety of transgenic organisms, horizontal gene transfer and expression of transgenes Kap. 25, pp 261-268. Schmidt ER, ed. Springer Heidelberg.
66     Bartsch J, Truss M, Bode J & Beato M (1996) Moderate histone acetylation activates the mouse mammary tumor virus promoter  and remodels its nucleosome structure. Proc. Natl. Acad. Sci.  USA  93:10741-10746. PDF
67     Schuebeler D, Mielke C, Maass K & Bode J (1996) Scaffold/Matrix-attached regions act upon transcription in a context-dependent manner. Biochemistry  35:11160-11169PDF
68     Schuebeler D, Mielke C & Bode J (1997) Excision of an integrated provirus by the action of Flp recombinase. In Vitro Cell. Dev. Biol. Anim.33:825-830.
69     Seibler J & Bode J (1997) Double-reciprocal crossover mediated by Flp-recombinase: a concept and an assay. Biochemistry 36:1740-1747PDF
70    Kohwi-Shigematsu T, Maass K & Bode J (1997)  A thymocyte factor, SATB1, suppresses transcription of stably integrated MAR-linked reporter genes. Biochemistry (accel. pub.) 36:12005-1210). PDF
71     Benham C, T. Kohwi-Shigematsu & Bode J (1997)  Stress Induced Duplex DNA Destabilization in Scaffold/ Matrix Attachment Regions. J. Mol. Biol. 272, 181-196. PDF (391 K)
72     Schuebeler D & Bode J (1997) . A sensitive transcription assay based on a simplified nuclear runon protocol.  Trends in Genetics 13:497 [http//]
73     Bode J, Bartsch J, Boulikas T,  Iber M, Mielke C, Schuebeler D, Seibler D & Benham C (1998). Transcription-Promoting Genomic Sites in Mammalia: Their Elucidation and Architectural Principles. In: “Textbook of Gene Therapy and Molecular Biology”, Gene Therapy and Molecular Biology Publications, T. Boulikas, ed., Gene Therapy Press, Athens, Greece pp 551-580. PDF
74     Seibler J, Schuebeler D, Fiering S, Groudine M & Bode J (1998) DNA cassette exchange in ES cells mediated by FLP recombinase: an efficient strategy for repeated modification of tagged loci by marker-free constructs. Biochemistry (accel. pub.) 37:6229-6234. PDF
75     Schuebeler D & Bode J (1998). Retargeting of retroviral integration sites for the predictable expression of transgenes and the analysis of cisacting sequences. Biochemistry 37, 11907-11914. PDF
76    Piechaczek C, Fetzer C,  Baiker A, Bode J & Lipps HJ (1999).  A vector based on the SV40 origin of replication and chromosomal S/MARs replicates episomally in CHO cells. Nucleic Acids. Res. 27: 426-428. Print PDF (116K)
77     Iber M, Schuebeler D, Seibler J, Hoexter M & Bode J (1999) Efficient FACS-selection procedure for cells undergoing Flp mediated site specific conversions. Trends in Genetics; TTO, 1999, 1:70:T01668 ( PDF [open access with permission by TIG ]
78     Bode J, Benham C, Knopp A & Mielke C (2000) Transcriptional augmentation: modulation of gene expression by scaffold/matrix attached Regions (S/MAR Elements). Crit. Rev. Eukaryot. Gene Expr. 10:73-90. PDF
79     Baiker A, Maercker C, Piechaczek C, Schmidt SBA, Bode J, Benham C & Lipps HJ (2000) Mitotic stability of S/MAR containing episomal vectors is provided by nuclear matrix association. Nature Cell Biology 2, 182-184. PDF
80     Baer A., Schuebeler D. &  Bode, J (2000). Transcriptional Properties of genomic transgene integration sites marked by electroporation or retroviral infection. Biochemistry 39, 7041-7049. PDF
81     Bode J, Schlake T, Iber M, Schuebeler D,  Seibler J, Snezhkov E & Nikolaev L (2000). The transgeneticistÂŽs toolbox:  novel methods for the targeted modification of eukaryotic genomes. Biol. Chem. 381:801-813. PDF
82     Bode J, Benham C, Ernst E, Knopp A, Marschalek R, Strick R & Strissel P (2000). Fatal connections: when DNA ends meet on the nuclear matrix. J. Cell. Biochem. 35, 3-22 PDF
83     Bode J, Fetzer CP, Nehlsen K, Scinteie M, Hinrich BH, Baiker A, Piechaczek C, Benham C & Lipps HJ (2001)  The hitchhiking principle: optimizing episomal vectors for the use in gene therapy and biotechnology. Gene Ther. Mol. Biol 6:33-46. PDF
84     Lipps HJ & Bode J (2001) Exploiting chromosomal and viral strategies: the design of safe and efficient nonviral gene transfer systems. Curr. Opin. Mol. Therapeut. 3:133-141. Scan
85    Baer A & Bode J (2001) . Coping with kinetic and thermodynamic barriers: RMCE, an efficient strategy for the targeted integration of transgenes”. Curr. Opin. Biotechnol. 12, 473-480. .
86   Engel H, Ruehl H, Benham CJ, Bode J & Weiss S (2001) Germline transcripts of the immunoglobulin lambda JC clusters in the mouse: Characterization of the initiation sites and regulatory elements. Mol. Immunol. 38:289-302.
87    Jenke BH, Fetzer CP, Jönsson F, Fackelmayer FO, Conradt HC, Bode J & Lipps HJ (2002) An episomally replicating vector binds to the nuclear matrix protein SAFA in vivo. EMBO Reports, 3, 349-354. PDF
88    Mielke C, Benham C, Bode J & Breindl M (2002) Nuclear matrix association potential of regulatory elements in the collagen 1a1 gene. J. Cell. Biochem. 84:484-496. PDF
89   Liebich I, Bode J, Frisch M & Wingender E (2002). S/MARt DB: A database on scaffold / matrix attached regions. Nucleic Acids Res. 30, 372-374. PDF
90    Liebich I, Bode J, Reuter I, Wingender E (2002). Evaluation of sequence motifs found in scaffold/matrix attached regions (S/MAR). Nucleic Acids Res. 15, 3433-3442. PDF
91    Dietz-Pfeilstetter A, Arndt N, Kay V & Bode J (2003). Molecular structure and regulatory potential of a TDNA integration site in petunia. Transgenic Res. 12, 83-99. PDF
92    Bode J, Goetze S, Ernst E, Huesemann Y, Baer A, Seibler J & Mielke C (2003) Architecture and utilization of highly-expressed genomic sites In: New Comprehensive  Biochemistry 38 / Gene Transfer and Expression in Mammalian Cells, Chap 20, pp551-572, Bernardi G, ed.; S. Makrides S, volume ed.
93     Gluch A, Benham C & Bode J (2003) Computational and in vitro analysis of destabilized DNA regions in the interferon gene cluster: the potential of predicting functional gene domains. Biochemistry 42, 154-166. PDF
94    Lipps HJ, Jenke ACW, Nehlsen K, Scinteie M, Stehle IM & Bode J (2003) Chromosome-based vectors for gene therapy. Gene 304:23-33. PDF
95   Bode J, Goetze S, H. Heng, S. A. Krawetz & Benham C (2003) From DNA structure to gene expression: mediators of nuclear compartmentalization and -dynamics.  Chromosome Res. 11:435-445
96    Goetze S, Y. Huesemann, A. Baer & Bode J (2003) Functional characterization of transgene integration patterns by halo-FISH: electroporation versus retroviral infection. Biochemstry 42:7035-7043. PDF
97     Cesari F, Rennekampff V, Vintersten K, Vuong L, Bode J, Seibler J, Wiebel FF & Nordheim A (2004). Site-directed mutagenesis of the murine Elk-1 locus by RMCE. Genesis 38:87-92. PDF
98     Heng HHQ, Goetze S, Ye CJ, Lu W, Liu G, Bremer S, Hughes M, Bode J & Krawetz SA (2004). Chromatin loops are selectively anchored using scaffold/matrix-attachment regions. J. Cell Sci. 117: 999-1008. PDF
99     Jenke, AW., Stehle IM., Eisenberger T, Baiker A, Bode J, Fackelmeyer, FO & Lipps HJ (2004) Nuclear scaffoldmatrix attached region modules linked to a transcription unit are sufficient for replication and maintenance of a mammalian episome. Proc. Natl. Acad. Sci. USA,101, 11322-11327. PDF
100    Vidakovic, M., Grdovic N, Quesada, P., Bode J & Poznanovic, G (2004) Poly(ADP-ribose) polymerase-1: association with nuclear lamins in rat hepatocytes. J. Cell. Biochem. 93, 1155-168. HTML PDF
101    Albrecht P., Bode J, Buiting K., AK P & Lohmann DR (2004). Recurrent deletion of a region containing exon 24 of the RB1 gene caused by non-homologous recombination between a LINE-1HS and MER21B element. J. Med. Genet. 41: e122. Full Text (PDF)
102  Goetze S, Baer A, Winkelmann S, Nehlsen K, Seibler J, Maass K & Bode J (2005) Genomic bordering elements: their performance at pre-defined genomic loci. Mol. Cell. Biol. 25: 2260-2272. Full Text (PDF)
103  Vidaković M, Koester M, Goetze S, Winkelmann S, Klar M, Poznanović G &  Bode J  (2005) Colocalization of PARP-1 and lamin B in the nuclear architecture: a halo-fluorescence- and confocal microscopy study . J. Cell. Biochem. 96:555-568. PDF Color Figures
104  Klar M., Stellamanns E, AK P, Gluch A & Bode J (2005). Dominant genomic structures: detection and potential signal functions, Gene, 364:79-89. PDF (648 K)
105  Vidaković M, Poznanović G & Bode J (2005) DNA break repair: refined rules of an already complicated game (2005) Biochem. Cell Biol./Biochim. Biol. Cell. 83:365-373 PDF Volume contents Volume introduction
106 Klar M & Bode J (2005) Enhanceosome formation over the interferon-beta promoter underlies a remote-control mechanism mediated by YY1 and YY2. Mol. Cell. Biol. 25: 10159-10170. Full Text (PDF)
107 Bode J, Winkelmann S, Goetze S, Spiker S, Tsutsui K, Bi C, AK P & Benham C (2006) Correlations between scaffold/matrix attachment region (S/MAR) binding activity and DNA duplex destabilization energy. J. Mol. Biol. 358:597-613,, PDF (524 K)
108 Oumard A, Qiao J, Jostock T, Li T & Bode J. (2006) Recommended Method for Chromosome Exploitation: RMCE-based cassette-exchange systems in animal cell biotechnology. Cytotechnology 50:93–108. PDF
109 Winkelmann S,  Klar M, Benham C, AK P, Goetze S, Gluch A &  Bode J (2006) The positive aspects of stress: Strain Initiates Domain Decondensation (SIDD). Briefings in Functional Genomics and Proteomics, 5, 24-31. PDF
110 Akopov SB., Ruda VM., Batrak VV, Vetchinova AS, Chernov  IP, Nikolaev LG,  Bode J. & Sverdlov ED (2006) Identification, genome mapping and CTCF binding of potential insulators within the FXYD5-COX7A1 locus of human chromosome 19q13.12. Mammalian Genome 17:1042-1049. PDF
111 Nehlsen K, Broll S & Bode J (2006) Replicating minicircles: Generation of nonviral episomes for the efficient modification of dividing cells. Gene Ther. Mol. Biol. 10:233-244. PDF
112 Linnemann AK, Platts AE, Doggett N, Gluch A., Bode J & Krawetz SA. (2007). Genome-wide identification of nuclear matrix attachment regions: an analysis of methods. Biochemical Society Transactions 35:612-617. PDF
113 Schneider B, Nagel S, Kaufmann M, Winkelmann S, Bode J, Drexler HG & MacLeod RAF (2007) t(3;7)(q27;q32) fuses BCL6 to a non-coding region at FRA7H near miR-29. Leukemia advance online publication, Nov 8,2007; doi:10.1038/sj.leu.2405025

114  Gluch A, Vidakovic M & Bode J (2008) Scaffold/matrix Attachment Regions (S/MARs): Relevance for Disease and Therapy, Protein-Protein Interactions as New Drug Targets / Handbook of Experimental Pharmacology 186, Klussmann E., Scott JD eds, Springer 2008, pp 67-103. PDF [ open access from this private homepage kindly permitted by Springer*) ]; regarding the series see:

115 Marella NRV, Zeitz MJ, Malyavantham KS, Pliss A, Matsui S, Goetze S, Bode J, Raska I & Berezney R (2008) Organization of the Type I IFN Gene Cluster in the Human Osteosarcoma Cell Line MG63. Chromosome Res. 16:1177–1192.
116 Zeitz MJ, Marella NRV, Malyavantham KS, Goetze S, Bode J, Raska I & Berezney R. (2009) Organization of the Amplified Type I Interferon Gene Cluster and Associated Chromosome Regions in the Interphase Nucleus of Human Osteosarcoma Cells., Chromosome Res. 2009;17:305-319
117 Vidakovic M, Gluch A, Poznanovic G & Bode, J. (2009) PARP-1 protein autoregulates its expression by binding to a recognition sequence and to an upstream S/MAR element in its own promoter. J. Mol. Biol. 388:730–750.
118 Qiao J, Oumard A, Wegloehner W & Bode J (2009) Novel Tag-and-Exchange (RMCE) Strategies Generate Master Cell Clones with Predictable and Stable Transgene Expression Properties. J. Mol. Biol. 390:579–594.
119 Iqbal K, Barg-Kues B, Broll S, Bode. J, Niemann H & Kues WA (2009) Reprogramming events in early embryos are reflected by circular plasmid encoded marker genes. BioTechniques 47, 959–968
120 Broll S, Oumard A, Hahn K, Schambach A & Bode J (2010) Minicircle Performance Depending on S/MAR-Nuclear Matrix Interactions. J. Mol.Biol. 395 (5), 950-965 
121 Voelkel C, Galla M., Maetzig T., Warlich E., Kuehle J., Zychlinski D, Bode, J, Cantz T, Schambach A, Baum C (2010) Retroviral polyprotein - mediated transduction of Flp recombinase. Proc. Natl. Acad. Sci. 107, 7805-7810
122 Turan S, Kuehle J, Schambach A,  Baum, C & Bode, J (2010) RMCE-multiplexing: versatile extensions of the Flp-Recombinase-Mediated Cassette-Exchange technology. J. Mol. Biol.  402 , 52-69.
123 Turan S, Galla M., Ernst E., Qiao J., Voelkel C, Schiedlmeier B, Zehe C & Bode J (2010) Recombinase-mediated cassette exchange (RMCE): traditional concepts and current challenges, J. Mol. Biol., 407(2):193-221 [9]
124 Turan, S. and Bode, J. (2011)  Site-specific recombinases: from tag-and-target- to tag-and-exchange-based genomic modifications FASEB J. 25, 4088-4107
125 Heinz N, Broll S,  Schleef  M, Baum C and Bode J (2012) Filling a gap: S/MAR-based replicating minicircles, CliniBook - Nonviral Platform; Clinigene Network pp271-277. EDP Sciences; ISBN 978-2-84254-171-2; EAN 9782842541712 PDF [Free access kindly permitted; EDK group EDP Sciences 25 rue Daviel 75013 PARIS (Copyright owner, Jan 12, 2012)]
126      Kober L, Zehe C & Bode J (2012) Development of a novel ER stress based selection system for the isolation of highly productive clones. Biotech. Bioeng.. 109(10), 2599-2611.  
127      Lars Kober1, Christoph Zehe2, Juergen Bode3 (2012) Optimized signal peptides for the development of high expressing CHO cell lines, Biotech. Bioeng. 109  
128      Doetsch M., Gluch A, Poznanović G, Bode J, Vidaković M (2012) YY1-binding sites provide central switch functions in the PARP-1 gene expression network. PLOS-one 7(8) e44125. .
129      Turan S, Zehe C, Kuehle J, Qiao J, Bode J. (2013) Recombinase-Mediated Cassette Exchange (RMCE) - a rapidly-expanding toolbox for targeted genomic modifications. Gene 515, 1–27.
130      Nehlsen K, Broll S, Kandimalla R, Heinz N, Heine M, Binius S, Schambach A & Bode J (2013) Replicating Minicircles: Overcoming the limitations of transient and of stable expression systems. In "Minicircle and Miniplasmid DNA Vectors - The Future of Non-viral and Viral Gene Transfer" 1st Edition, pp115-162, Schleef, M. (ed.), ISBN 978-3-527-32456-9 - Wiley-VCH, Weinheim.



*) Dear Prof. Juergen Bode,

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Berichte und populÀrwissenschaftliche Artikel

  • Kues W, Niemann H, Iqbal K, Garrels W & Bode J (2009) Nonviral episomes permit targeted expression in mammalianembryos. REBIRTH Newsletter 03-09, 6-7. PDF
  • S. Broll, K. Nehlsen & J. Bode (2007) Kleine Kreise mit großem Potenzial. Chem. Rundschau 2007 (1-2), 40-41.
  • J. Bode (2003) Vektor-Design: Die funktionelle Organisation der Gene als Lehrmeister in  ”Gendoping - die DopingbekĂ€mpfung rĂŒstet sich” Bundesinstitut fĂŒr Sportwissenschaft: Wissenschaftliche Berichte und Materialien Band 07, pp 53-64, Wolfgang Hartmann, Red (Berichte von der 5. Dopingkleinkonferenz, 10. Jul. 2002, Bundesinstitut fĂŒr Sportwissenschaft, 53177 Bonn)   Besprechung; PDF
  • S. Goetze, M. Klar, K. Maass, K. Nehlsen, A. Oumard, S. Winkelmann & J. Bode (2004) Den Viren nachempfunden: Effiziente Modifikation von SĂ€ugerzellen BIOforum 1-2, 34-36.


  • Broll S, Nehlsen K & Bode J (2007) Replicating Non-Viral Minicircles: Novel Tools for Predictable Transgenesis. Hum Gene Ther.18(10), 950 (Inv 26)
  • Broll S, Nehlsen K, Oumard A & Bode J (2007) S/MARs enable the generation of nonviral replicating minicircles. Transgenic Research 16(6), Abstract UC Davis Transgenic Animal Research Conference VI, 839-863 
  • Broll S, Bode J & Goetze S (2008) Prediction of gene-regulatory and replication functions by SIDD structure analysis. Hum. Gene Ther. 19(10), 1071-1072 (Inv 44)
  • KymĂ€lĂ€inen HE, Bode J, Foster K, Yanez-Munoz RJ & Dickson GP (2009) Stress-Induced Duplex Destabilisation: An In Silico and In Culture Analysis of Viral Vector Genomes Incorporating S/MAR Elements. Hum. Gene Ther. 20, P63
  • Wagner S, McCracken J, Bruszies S, Oswald, J, Oback B, Bode J & Laible S (2010) Minicircle episomal plasmids are stably transmitted in bovine fibroblasts. UC Davis Transgenic Animal Research Conference VII; Aug.17-22 Lake Tahoe. Transgenic Res  19:152–153. DOI 10.1007/s11248-009-9326-4
  • Rehberger, B., Heine, M., Wodarczyk, C., Wirth, M., Bode, J. & Wagner, R. (2011) ‘MiniCircles’ - New Horizons for Stable Recombinant Protein Expression? PDF
  • Heine, M., Rehberger, B., Wodarczyk, C., Wirth, M., Bode, J. & Wagner, R. (2011)  Simplify your ‘MiniCircle’ Production: A New Semi-synthetic Process for Manufacturing MiniCircle. PDF
    both: ESACT Wien. Mai 15-18, 2011, “Cell Based Technologies”
  • J Bode, N Heinz, K. Nehlsen, S Broll, S. Wagner, G Laible, W Kues, A Athanassiadou, M Schleef. Replicating minicircles: Overcoming the limitations of transient and stable expression system (Or29)
  • S Turan, J Kuehle, A Schambach, C Baum, J Bode. Versatile Extensions of the Flp-Recombinase-Mediated Cassette Exchange Technology: multiplexing RMCE meets the needs for predictable genome engineering (P59)
    both: European Society of Gene and Cell Therapy British Society for Gene Therapy Collaborative Congress ESACT 2011, Brighton (HUMAN GENE THERAPY 22:2, 2011) DOI: 10.1089/hum.2011.2525


  • J. Bode, J. Seibler and D. Schuebeler (1998-2005) EuropĂ€ische Patentanmeldung 98 103 490.3. DNA cassette exchange in regenerative vertebrate cells.
  • J, Bode, J. Seibler and D. Schuebeler (2005) Methods for marker-free repetitive DNA expression of cassette exchange in the genome of cells or parts of cells EP0939120, US20010032341, CA2263482, JP2000023679
  • Baiker, A., Bode, J., Fetzer, C., Lipps, H. J. & Piechaczek, C. (Deutsche und Internationale Patentanmeldung 10078487 / 1999) Episomal replizierender Vektor zur permanenten Expression eines Transgens in SĂ€ugerzellen.
  • Baiker, A., Stehle, I., Bode, J. & Lipps, H. J. (Deutsche und Internationale Patentanmeldung 2003) Synthetischer, episomal replizierender und mitotisch stabiler Vektor als Expressionssystem fĂŒr SĂ€ugerzellen.EuropĂ€ische Patentanmeldung 103 29 027.3-41.


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